Combining Complete Blood Count with Differential Count; C-Reactive Protein and Band Neutrophils in Diagnosis of Early onset Neonatal Sepsis

Aim: To assess the diagnostic accuracy of complete blood count with band versus total neutrophil ratio and C-reactive proteins as an efficient analytical procedure for determining early onset sepsis in neonates. Study design: Cross sectional study Place duration study: Department Paediatric Medicine, Abbas Institute Medical Sciences Muzafarabad, AJ Kashmir from 01-02-2022 to 31-07-2022. Methodology: Fifty patients were enrolled. Coulter counter was used analyzing leucocytes Thin film-smears generated by laboratory scientist identifying neutrophils separately mature neutrophils. level <5mg/dl considered negative. Thio-glycate-oxide liquid form 2ml neonatal culture analysis mixed 20ml medium at 36 degree celsius. Results: There 28 (56%) males 22 (44%) females. The mean age neonates 1.6± 0.77 days. weight 2.4±0.51kg a range 4-1.2kg. A variance significantly higher cultures which positive than negative such 70% vs 25%. also significant percentage comparison culture. Conclusion: combination differential count, white cell c-reactive is gold standard test time taking. Key Words: Complete protein, Total ratio, Early sepsis.